Treating Sarcoma (Including Gist) Subtypes Based on Molecular Characteristics

An Educational Service for Medical Oncologists, Gastroenterologists and other GIST Care Providers Impact of Molecular Subtypes on Resistance to Therapy New Perspectives on Genetics of GIST Lacking KIT, PDGFRA Mutations Surgery in Metastatic GIST: Optimizing Outcomes

Consensus Molecular Subtypes of Colorectal Cancer and their Clinical Implications

The colorectal cancer (CRC) subtyping consortium has unified six independent molecular classification systems, based on gene expression data, into a single consensus system with four distinct groups, known as the consensus molecular subtypes (CMS); clinical implications are discussed in this review based on articles relevant to the CMS of CRC indexed in PubMed as well as the authors’ own ...

First report of Tuber aestivum var. uncinatum from Iran based on morphological and molecular characteristics

Truffles are the most delicious, rare and most expensive edible fungi in the world. Interest on truffles has continuously grown in Iran during the past two decades. The oldest data on Iranian truffles were reported by Chatin who proposed the names Terfezia aphroditis Chatin and T. hanotauxii Chatin for samples collected in Iran (Chatin 1897, Esfandiari & Petrak 1950).During the last 70 years, s...

Consensus on Molecular Subtypes of Ovarian Cancer

INTRODUCTION: Various computational methods for gene expression-based subtyping of highgrade serous (HGS) ovarian cancer have been proposed. This resulted in the identification of molecular subtypes that are based on different datasets and were differentially validated, making it difficult to achieve consensus on which definitions to use in follow-up studies. We assess three major subtype class...

Incidence of Sarcoma Histotypes and Molecular Subtypes in a Prospective Epidemiological Study with Central Pathology Review and Molecular Testing

BACKGROUND The exact overall incidence of sarcoma and sarcoma subtypes is not known. The objective of the present population-based study was to determine this incidence in a European region (Rhone-Alpes) of six million inhabitants, based on a central pathological review of the cases. METHODOLOGY/PRINCIPAL FINDINGS From March 2005 to February 2007, pathology reports and tumor blocks were prosp...